Coordination of Amino Acid Side Chains in Metalloproteins
In many metalloproteins, the functinal groups of amino acids are used to bind metal ions. This coordination often occurs together with other physiological complexing agents such as porphyrins or corrins.
Common amino acids for this coordination are histidine, cysteine, methionine or aspartic acid.
Examples:
Histidine |
Azurin (detail) |
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Metal center:Cu(His)2(Cys)(Met)(OR) |
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Function:Bacterial photosynthesis |
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To the examples for: Cysteine, Methionine, Aspartic Acid.