Coordination of Amino Acid Side Chains in Metalloproteins
In many metalloproteins, the functinal groups of amino acids are used to bind metal ions. This coordination often occurs together with other physiological complexing agents such as porphyrins or corrins.
Common amino acids for this coordination are histidine, cysteine, methionine or aspartic acid.
Examples:
Cysteine |
Iron Clusters |
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Metal center:Fe2(Cys)4S2 and others |
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Function:Electron transfer |
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Iron Clusters Zinc finger Azurin |
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To the examples for: Histidine, Methionine, Aspartic Acid.