Cytochrome c-oxidase is a very important, but very complex metalloenzyme. It contains protein bound copper and magnesium ions as well as iron haem centers.
It is situated in a membrane as the last member of the respiratory chain, which allows a controlled separation (separate transport of e- and H+) during the relevant redox process.
This function is made possible by the exact spatial arrangement of the metal centers.
Spacial arrangement of the metal centers